Diagnosis of Trisomy 18 Using Spontaneously Dividing Cells from Fetal Umbilical Cord Blood: A Novel Approach for Rapid Late Second and Third Trimester Prenatal Diagnosis

Autor:	Joe Leigh Simpson, Michael Moretti, Carole M. Meyers, Lee P. Shulman, R. S. Wilroy, John Summitt, Sherman Elias, Robert E. Tipton, Michael Epps, Avirachan T. Tharapel
Rok vydání:	1990
Předmět:	Adult medicine.medical_specialty Pregnancy Trimester Third Aneuploidy Trisomy Prenatal diagnosis Umbilical cord Pregnancy Prenatal Diagnosis medicine Humans Abnormalities Multiple Fetus Fetal Growth Retardation Obstetrics business.industry Obstetrics and Gynecology Fetal Blood medicine.disease medicine.anatomical_structure In utero Pregnancy Trimester Second Cord blood Pediatrics Perinatology and Child Health Female Chromosomes Human Pair 18 business
Zdroj:	American Journal of Perinatology. 7:211-213
ISSN:	1098-8785 0735-1631
DOI:	10.1055/s-2007-999483
Popis:	Cytogenetic methodology recently developed by us allows spontaneously dividing cells in fetal cord blood to be used for rapid (24 hours) chromosome analysis. We utilized this methodology to diagnose trisomy 18 and facilitate clinical management in a 32-week pregnancy characterized by multiple fetal anomalies and intrauterine growth retardation.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bf987c93ca312f58b9901f0da4d3c17 https://doi.org/10.1055/s-2007-999483 Zobrazit plný text záznamu