Muscle hypertrophy in cancer patients and survivors via strength training. A meta-analysis and meta-regression
| Autor: | Joachim Wiskemann, Kathryn H. Schmitz, Katlynn Mathis, Maximilian Koeppel |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
0301 basic medicine
medicine.medical_specialty Strength training Cochrane Library Muscle hypertrophy 03 medical and health sciences 0302 clinical medicine Neoplasms Internal medicine medicine Humans Muscle Strength Survivors Muscle Skeletal Wasting business.industry Muscles Cancer Resistance Training Hypertrophy Hematology medicine.disease 030104 developmental biology Oncology 030220 oncology & carcinogenesis Sarcopenia Meta-analysis Lean body mass medicine.symptom business |
| Zdroj: | Critical Reviews in Oncology/Hematology. 163:103371 |
| ISSN: | 1040-8428 |
| Popis: | Background Muscle wasting has a negative effect on treatment toxicity and cancer prognosis. Resistance training appears to be a promising approach to counteract the loss of muscle mass. Methods Pubmed, Cochrane Library, SportDiscus and CINAHL. Randomized controlled resistance training trials with cancer survivros where eligible if lean body mass (LBM) or muscle mass were assessed. Results A total of 34 trials were included into the primary analysis. Compared to the control individuals, the intervention groups show a superiority in LBM of 0.85 kg (95 % CI = 0.26–1.43, p = .004). Isolated, the participants in the intervention groups show an increase in LBM of 0.51 kg (95 % CI = −0.05–1.06, p = .072); the control groups displayed a decrease of −0.59 kg (95 % CI= −1.04 to 0.06, p = .078). Supervision displayed an mediating role. Conclusions Resistance training can counteract the loss of muscle mass in cancer patients. Especially in a supervised setting. |
| Databáze: | OpenAIRE |
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