Clinical impact and direct costs of nosocomial respiratory syncytial virus infections in the neonatal intensive care unit
| Autor: | Andreu Comas-García, Francisco J. Escalante-Padrón, Daniel E. Noyola, Luis Meave Gutiérrez-Mendoza, José I. Aguilera-Martínez, Victoria Lima-Rogel |
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| Rok vydání: | 2019 |
| Předmět: |
Pediatrics
medicine.medical_specialty Neonatal intensive care unit Epidemiology medicine.medical_treatment Birth weight Respiratory Syncytial Virus Infections 03 medical and health sciences Indirect costs 0302 clinical medicine Intensive care Intensive Care Units Neonatal Medicine Humans 030212 general & internal medicine Mexico Retrospective Studies Mechanical ventilation 0303 health sciences Cross Infection 030306 microbiology business.industry Health Policy Incidence (epidemiology) Public Health Environmental and Occupational Health Infant Newborn Gestational age Infant Retrospective cohort study Hospitalization Infectious Diseases business |
| Zdroj: | American journal of infection control. 48(9) |
| ISSN: | 1527-3296 |
| Popis: | Nosocomial infections are a leading cause of morbidity, costs, and mortality in preterm newborns. Most reports regarding nosocomial infections in neonatal intensive care units (NICU) are focused on bacterial infections and there is limited information regarding the impact of nosocomial viruses. The objective of this study was to assess the impact of nosocomial respiratory syncytial virus (RSV) infections in a NICU.This was a retrospective cohort design from a NICU in a general hospital in Mexico. We included 24 newborn infants with nosocomial RSV infection and 24 infants without RSV matched by gestational age, birth weight, and the period of time of hospitalization.Infants with nosocomial RSV infection had longer hospitalization duration (median 24 days vs. 13 days; P = .05), increased antibiotic use (45.8% vs. 8.3%; P = .003), more mechanical ventilation requirement (54.2% vs. 0.4%; P.001), more frequent nosocomial infections (45.8% vs. 0%; P.001), and higher hospitalization direct costs (median 3,587.20 USD vs. 1,123.60 USD; P = .001) after nosocomial RSV detection.Nosocomial RSV infections are associated to a significant increase of costs in infants hospitalized in the NICU. Evaluation of interventions that may reduce the incidence of nosocomial RSV infections in this setting is warranted. |
| Databáze: | OpenAIRE |
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