Challenges for the Implantation of Symbiotic Nanostructured Medical Devices
| Autor: | Jacques Thélu, Philippe Cinquin, Sarra El Ichi, Donald K. Martin, Abdelkader Zebda, Jean-Pierre Alcaraz, Geraldine Penven, Gauthier Menassol |
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| Přispěvatelé: | Systèmes Nanobiotechnologiques et Biomimétiques (TIMC-IMAG-SyNaBi), Techniques de l'Ingénierie Médicale et de la Complexité - Informatique, Mathématiques et Applications Grenoble - UMR 5525 (TIMC-IMAG), VetAgro Sup - Institut national d'enseignement supérieur et de recherche en alimentation, santé animale, sciences agronomiques et de l'environnement (VAS)-Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes (UGA)-Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP ), Université Grenoble Alpes (UGA)-VetAgro Sup - Institut national d'enseignement supérieur et de recherche en alimentation, santé animale, sciences agronomiques et de l'environnement (VAS)-Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes (UGA)-Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP ), Université Grenoble Alpes (UGA), Neurodegenerescence et Plasticite, Université Joseph Fourier - Grenoble 1 (UJF)-Institut National de la Santé et de la Recherche Médicale (INSERM) |
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
Medical device
[SDV.BIO]Life Sciences [q-bio]/Biotechnology Biocompatibility Computer science Duplex (telecommunications) 02 engineering and technology 010402 general chemistry 01 natural sciences nanobiotechnology lcsh:Technology lcsh:Chemistry biocompatibility Human–computer interaction General Materials Science Instrumentation lcsh:QH301-705.5 Implanted device ComputingMilieux_MISCELLANEOUS Fluid Flow and Transfer Processes lcsh:T Process Chemistry and Technology General Engineering 021001 nanoscience & nanotechnology lcsh:QC1-999 0104 chemical sciences Computer Science Applications lcsh:Biology (General) lcsh:QD1-999 bioinspiration lcsh:TA1-2040 symbiotic Bioinspiration 0210 nano-technology lcsh:Engineering (General). Civil engineering (General) Biofuel Cells lcsh:Physics implanted medical device |
| Zdroj: | Applied Sciences Applied Sciences, MDPI, 2020, 10 (8), pp.2923. ⟨10.3390/app10082923⟩ Applied Sciences, Vol 10, Iss 2923, p 2923 (2020) |
| ISSN: | 2076-3417 |
| DOI: | 10.3390/app10082923⟩ |
| Popis: | We discuss the perspectives of designing implantable medical devices that have the criterion of being symbiotic. Our starting point was whether the implanted device is intended to have any two-way (“duplex”) communication of energy or materials with the body. Such duplex communication extends the existing concepts of a biomaterial and biocompatibility to include the notion that it is important to consider the intended functional use of the implanted medical device. This demands a biomimetic approach to design functional symbiotic implantable medical devices that can be more efficient in mimicking what is happening at the molecular and cellular levels to create stable interfaces that allow for the unfettered exchanges of molecules between an implanted device and a body. Such a duplex level of communication is considered to be a necessary characteristic of symbiotic implanted medical devices that are designed to function for long periods of time inside the body to restore and assist the function of the body. We illustrate these perspectives with experience gained from implanting functional enzymatic biofuel cells. |
| Databáze: | OpenAIRE |
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