Pre- and postpartum supplemental DL-alpha-tocopheryl acetate effects on placental and mammary vitamin E transfer in sheep
| Autor: | S B Linda, S N Williams, Lee Russell McDowell, N.S. Wilkinson, C A Njeru |
|---|---|
| Rok vydání: | 1994 |
| Předmět: |
medicine.medical_specialty
medicine.medical_treatment Placenta Mammary gland alpha-Tocopherol Tocopherols Dl-alpha tocopheryl acetate Antioxidants Random Allocation Animal science Mammary Glands Animal Pregnancy Internal medicine Genetics medicine Animals Vitamin E Treatment effect Tocopherol Volume concentration Analysis of Variance Sheep Dose-Response Relationship Drug Chemistry Colostrum Postpartum Period General Medicine Animal Feed medicine.anatomical_structure Endocrinology Milk Food Fortified Animal Science and Zoology Female Food Science |
| Zdroj: | Journal of animal science. 72(6) |
| ISSN: | 0021-8812 |
| Popis: | Twenty-six pregnant ewe lambs were used to study the effect of four treatment (T 1 to 4) levels of DL-alpha-tocopheryl acetate (0, 15, 30, and 60 IU.lamb-1.d-1) supplemented 28 d prepartum through 28 d postpartum on placental and mammary gland transfer of alpha-tocopherol. Blood samples were first obtained on d 28 prepartum and thereafter with milk samples at designated intervals up to 28 d postpartum for alpha-tocopherol analyses. Similarly, blood samples were obtained from neonatal lambs on d 1 before suckling and on d 3, 14, and 28 postpartum. Ewe lamb serum tocopherol concentrations averaged .66 micrograms/mL before T administration; 28 d later averages were .93, 1.94, 2.63, and 4.07 micrograms/mL (linear, P.05) for T 1 to 4, respectively. Supplemental vitamin E had no effect (P.05) on serum alpha-tocopherol of neonatal lambs, indicating inefficient placental transfer. By d 3, lamb serum tocopherol increased to 1.41, 1.84, 2.43, and 4.46 micrograms/mL (linear, P.05) for T 1 to 4 following consumption of colostrum and declined to .46, .74, 1.10, and 1.68 micrograms/mL (linear, P.05) by d 28. On d 1 there was a linear (P.05) treatment effect on tocopherol in colostrum, with a low concentration of 3.30 micrograms/mL for the control (T 1) and a high of 9.55 micrograms/mL for T 4.(ABSTRACT TRUNCATED AT 250 WORDS) |
| Databáze: | OpenAIRE |
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