Role of food-drug interactions in neurological and psychological diseases
| Autor: | Fatma Zehra Kadayifçi, Ozge Yesildemir, Yasemin Ertaş Öztürk, Makbule Gezmen-Karadag, Duygu Ağagündüz, Elif Celik |
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| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: |
0301 basic medicine
Drug biology business.industry General Neuroscience media_common.quotation_subject digestive oral and skin physiology Food-Drug Interactions Appetite General Medicine Gut flora Body weight biology.organism_classification Bioinformatics 03 medical and health sciences 030104 developmental biology 0302 clinical medicine Pharmacokinetics Medicine In patient business Drug toxicity 030217 neurology & neurosurgery media_common |
| Popis: | Given that foods and nutrients have been shown to influence the pharmacokinetics of drugs, drugs may cause changes in the nutritional status of patients and their response to a given drug. Food‑drug interactions are particularly relevant for drugs used to treat neurological and psychological diseases. This review provides an overview of food‑drug interaction in the treatment of neurological and psychological diseases. A literature search was carried out by collecting data from different reviews, reports, and original articles on general or specific drug interactions with food, in patients with a variety of neurological and psychological diseases. Based on our review, we found that food‑drug interactions may alter the expected impact of drug, or cause the development of a drug toxicity. Nutritional status of the patients may also be affected, particularly a change in body weight caused by a change appetite. Metabolism, absorption, and excretion of foods may also be altered, and nutritional insufficiencies may occur. Recent studies show that diet can have a strong influence on gut microbiota and thus, alter drug pharmacokinetics. Therefore, microbiota alterations should also be considered while assessing food‑drug interactions. Knowledge of food‑drug interactions is critical for improving health of patients with neurological and psychological diseases, and also for improving effectiveness of treatments. |
| Databáze: | OpenAIRE |
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