Abdominal Aortic Disease Caused by Penetrating Atherosclerotic Ulcers
| Autor: | Masataka Sato, Tomoaki Jikuya, Akito Imai, Yasunori Watanabe, Hiroaki Sakamoto, Akinobu Sasaki |
|---|---|
| Rok vydání: | 2012 |
| Předmět: |
Aortic dissection
medicine.medical_specialty Aorta business.industry Abdominal aorta General Medicine Dissection (medical) medicine.disease Asymptomatic Surgery Aortic aneurysm Penetrating atherosclerotic ulcer medicine.artery cardiovascular system medicine Original Article Radiology medicine.symptom business Aortic rupture |
| Zdroj: | Annals of Vascular Diseases. 5:8-14 |
| ISSN: | 1881-6428 1881-641X |
| DOI: | 10.3400/avd.oa.11.00916 |
| Popis: | Objective: Penetrating atherosclerotic ulcer (PAU) of the aorta is defined as an atherosclerotic lesion with ulceration of the aortic intima and media and rupture of the internal elastic lamina. PAU induced aortic dissection, aortic rupture, and secular aortic aneurysm and typically occurs in elderly hypertensive patients with severe atherosclerosis. Although it has been reported that atherosclerosis similarly occurs in the abdominal aorta, its natural history and treatment are still unclear. This study investigated the clinical features, natural history, and treatment of PAU of the abdominal aorta. Method:Between April 2006 and March 2009, 4 diagnoses of PAU in the abdominal aorta were made by computed tomography (CT) and magnetic resonance imaging (MRI). These 4 cases were analyzed along with 61 previously reported cases from the literature with diagnoses of PAU in the abdominal aorta, aortic rupture, and isolated abdominal aortic dissection over the past 15 years, giving a total of 65 cases. Results:The patients were men with an average age of 63.5 years. All 4 had hypertension, and 2 had concomitant coronary artery disease. Two patients were asymptomatic, and the other 2 were symptomatic and transmural rupture had occurred. All diagnoses were made by CT and MRI. All 4 patients underwent open surgery with a knitted Dacron graft, with no postoperative deaths. In the literature, 53% of cases were symptomatic, including pain (40%, n = 26), shock (4.6%, n = 3), and lower limb embolism (9.2%, n = 6). The remaining 40% of cases were asymptomatic (n = 26). Six patients were treated medically, while 58 patients underwent surgery, with 2 postoperative deaths. Conclusion:We suggest that surgical treatment (open surgery or endovascular stent grafting) should be performed to prevent an aortic catastrophe such as intramural hematoma, dissection, or rupture. (English translation of Jpn J Vasc Surg 2010; 19: 723-730.) |
| Databáze: | OpenAIRE |
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