Methotrexate Use and Monitoring in Patients with Psoriasis: A Consensus Report Based on a Danish Expert Meeting

Autor: Michael Heidenheim, Lars Iversen, Line Raaby, Anne T. Funding, Lone Skov, Jakob Torp Madsen, Monika Østensen, Peter Thielsen, Gitte Strauss, Rune Lindberg, Henning Grønbæk, Nini Kyvsgaard, Lene Heickendorff, Claus Zachariae
Rok vydání: 2017
Předmět:
Male
0301 basic medicine
Pathology
Time Factors
Denmark
Alternative medicine
Nice
030207 dermatology & venereal diseases
0302 clinical medicine
Liver Function Tests
Pregnancy
Risk Factors
immune system diseases
Neoplasms
Drug Dosage Calculations
Child
skin and connective tissue diseases
media_common
computer.programming_language
Age Factors
General Medicine
Treatment Outcome
Female
Patient Safety
Chemical and Drug Induced Liver Injury
Risk assessment
Immunosuppressive Agents
Adult
musculoskeletal diseases
medicine.medical_specialty
Consensus
media_common.quotation_subject
MEDLINE
Dermatology
Risk Assessment
03 medical and health sciences
Patient safety
Excellence
Psoriasis
Journal Article
medicine
Humans
business.industry
Guideline
medicine.disease
Pregnancy Complications
Methotrexate
030104 developmental biology
Family medicine
business
computer
Zdroj: Raaby, L, Zachariae, C, Østensen, M, Heickendorff, L, Thielsen, P, Grønbæk, H, Skov, L, Kyvsgaard, N, Madsen, J T, Heidenheim, M, Funding, A T, Strauss, G, Lindberg-Larsen, R & Iversen, L 2017, ' Methotrexate Use and Monitoring in Patients with Psoriasis : A Consensus Report Based on a Danish Expert Meeting ', Acta Dermato-Venereologica, vol. 97, no. 4, pp. 426-432 . https://doi.org/10.2340/00015555-2599
Raaby, L, Zachariae, C, Østensen, M, Heickendorff, L, Thielsen, P, Grønbæk, H, Skov, L, Kyvsgaard, N, Madsen, J T, Heidenheim, M, Funding, A T, Strauss, G, Lindberg, R & Iversen, L 2017, ' Methotrexate Use and Monitoring in Patients with Psoriasis : A Consensus Report Based on a Danish Expert Meeting ', Acta Dermatovenereologica, vol. 97, pp. 426–432 . https://doi.org/10.2340/00015555-2599
ISSN: 0001-5555
DOI: 10.2340/00015555-2599
Popis: Methotrexate (MTX) has been used in the treatment of psoriasis and other dermatological diseases for more than 50 years. However, there is limited evidence regarding its effect, dose and monitoring, and a lack of consensus regarding how the drug should be used in daily practice. Although the use of MTX is governed by guidelines, such as the European S3-Guidelines and the National Institute for Health and Care Excellence (NICE) guideline, it is important to discuss and adjust these guidelines to national standards. An expert meeting was held in Denmark at the end of 2014, in order to reach consensus regarding the use of MTX in dermatological practice in Denmark. Participants included dermatologists, hepatologists, paediatricians, clinical biochemists and a rheumatologist. Topics discussed were: liver disease monitoring, teratogenic effects of MTX, risk of cancer, and use of MTX in children. We report here the conclusions of this expert meeting regarding use of MTX in dermatological practice. Methotrexate (MTX) has been used in the treatment of psoriasis and other dermatological diseases for more than 50 years. However, there is limited evidence regarding its effect, dose and monitoring, and a lack of consensus regarding how the drug should be used in daily practice. Although the use of MTX is governed by guidelines, such as the European S3-Guidelines and the National Institute for Health and Care Excellence (NICE) guideline, it is important to discuss and adjust these guidelines to national standards. An expert meeting was held in Denmark at the end of 2014, in order to reach consensus regarding the use of MTX in dermatological practice in Denmark. Participants included dermatologists, hepatologists, paediatricians, clinical biochemists and a rheumatologist. Topics discussed were: liver disease monitoring, teratogenic effects of MTX, risk of cancer, and use of MTX in children. We report here the conclusions of this expert meeting regarding use of MTX in dermatological practice.
Databáze: OpenAIRE