Peripheral arterial thrombolysis: Intermediate-term results
| Autor: | G. S. Makin, R.H.S. Gregson, S.C. Whitaker, D. C. Berridge, P.W. Wenham, Brian R. Hopkinson, R. J. Lonsdale, J. J. Earnshaw |
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| Rok vydání: | 1993 |
| Předmět: |
Adult
Male medicine.medical_specialty Time Factors medicine.medical_treatment Ischemia Arterial Occlusive Diseases Asymptomatic Risk Factors medicine Humans Thrombolytic Therapy Vascular Patency Aged Aged 80 and over Intermediate term Leg Chemotherapy Vascular disease business.industry Thrombolysis Middle Aged medicine.disease Peripheral Surgery Treatment Outcome Amputation Anesthesia Female medicine.symptom business |
| Zdroj: | British Journal of Surgery. 80:592-595 |
| ISSN: | 1365-2168 0007-1323 |
| Popis: | To determine the intermediate-term results of intra-arterial thrombolysis, 127 consecutive patients receiving 129 courses of treatment were reviewed at a median follow-up of 3 years. At initial review, 30 days after treatment, thrombolysis was successful in 63 cases (49 per cent). Of these patients, 16 were lost to follow-up: 15 died without further vascular symptoms and one moved from the area. Some 35 patients were alive and asymptomatic, of whom 33 had either angiographic or clinical evidence of continued arterial patency. Symptomatic reocclusion occurred in 12 cases; a further two patients remained asymptomatic and reocclusion was detected at follow-up. Two of the 12 symptomatic patients required amputation. Estimated patency rates were 80 per cent at 1 year, 72 per cent at 2 years and 70 per cent at 3 years. The intermediate-term results in the 66 cases in which lysis was unsuccessful were worse, only 16 patients (24 per cent) surviving to follow-up with the treated limb intact. It is concluded that, if thrombolysis is successful at 30 days, the intermediate-term results are good. |
| Databáze: | OpenAIRE |
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