Vital exhaustion, extent of atherosclerosis, and the clinical course after successful percutaneous transluminal coronary angioplasty
| Autor: | H. De Swart, Ad Appels, Willem J. Kop, C. F. Mendes de Leon, Frits W. Bär |
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| Rok vydání: | 1995 |
| Předmět: |
Adult
Male medicine.medical_specialty medicine.medical_treatment Myocardial Infarction Coronary Artery Disease Angina Coronary artery disease Coronary artery bypass surgery Recurrence Risk Factors Angioplasty Internal medicine medicine Humans Treatment Failure cardiovascular diseases Myocardial infarction Angioplasty Balloon Coronary Coronary Artery Bypass Fatigue Aged business.industry Odds ratio Middle Aged medicine.disease Death Sudden Cardiac Cardiology Myocardial infarction diagnosis Cardiology and Cardiovascular Medicine business Follow-Up Studies Vital Exhaustion |
| Zdroj: | European Heart Journal. 16:1880-1885 |
| ISSN: | 1522-9645 0195-668X |
| DOI: | 10.1093/oxfordjournals.eurheartj.a060842 |
| Popis: | It has been observed that vital exhaustion, a state characterized by unusual tiredness, increased irritability and feelings of demoralization not uncommonly precedes myocardial infarction in apparently healthy individuals. This observation raised the question as to whether vital exhaustion is a marker of subclinical coronary disease. To answer that question the condition was assessed in 105 male patients (mean age 54.8 year) before and 2 weeks after successful percutaneous transluminal coronary angioplasty (PTCA) by the Maastricht questionnaire. Vital exhaustion was found to be significantly correlated with the number of diseased vessels before PTCA and to decrease significantly after PTCA. However, the association was rather modest (R2 = 0.08) and most patients remained exhausted after PTCA. During a follow-up period of 1.5 years, 32 patients (30%) experienced a new cardiac event (cardiac death, myocardial infarction, coronary artery bypass grafting, repeat PTCA, a new coronary lesion or recurrent angina with documented ischaemia). Univariate and multivariate analyses showed that the number of diseased vessels, hypercholesterolaemia, and vital exhaustion were independently associated with future events. The odds ratios were 3.74 (P = 0.02), 3.08 (P = 0.08) and 3.07 (P = 0.04), respectively. It is concluded that the tiredness preceding a cardiac event is only modestly associated with the extent of coronary artery disease and that a state of exhaustion after PTCA increases the risk for a new cardiac event. |
| Databáze: | OpenAIRE |
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