Severe medication-induced peripheral neuropathy treated with topical doxepin cream in a paediatric patient with leukaemia
| Autor: | Jenny Kim, Dennis John Kuo, Zephyr D Dworsky, Rebecca Bennett |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
medicine.medical_specialty
Adolescent Side effect Administration Topical Severity of Illness Index Disease course 03 medical and health sciences 0302 clinical medicine Refractory 030202 anesthesiology medicine Humans Mucormycosis Topical doxepin Novel Treatment (New Drug/Intervention Established Drug/Procedure in New Situation) Paediatric patients Dosage Forms business.industry Peripheral Nervous System Diseases General Medicine Precursor Cell Lymphoblastic Leukemia-Lymphoma medicine.disease Dermatology Peripheral neuropathy Lymphoblastic leukaemia Female Doxepin business 030217 neurology & neurosurgery |
| Zdroj: | BMJ Case Reports. :bcr-2017 |
| ISSN: | 1757-790X |
| DOI: | 10.1136/bcr-2017-219900 |
| Popis: | A 17-year-old female with recently relapsed acute lymphoblastic leukaemia and a treatment course complicated by rhinocerebral mucormycosis infection developed severe peripheral neuropathy during the treatment for mucormycosis infection. This was felt to be a medication side effect. Her peripheral neuropathy was refractory to many well-established treatments, but ultimately responded dramatically and consistently to a novel therapy, topical doxepin cream (5%). This case report is the first published report of the application of topical doxepin cream for treatment of peripheral neuropathy in a paediatric patient. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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