Clinical Characteristics of Alternaria Keratitis
| Autor: | Hsin-Chiung Lin, David Hui-Kang Ma, Ching-Hsi Hsiao, Phil Y. F. Chen, Hung-Chi Chen, Hsin-Yuan Tan, Lung-Kun Yeh |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2014 |
| Předmět: |
medicine.medical_specialty
Article Subject Mycotic keratitis biology business.industry Ocular surgery Perforation (oil well) medicine.disease Alternaria biology.organism_classification Dermatology Keratitis Surgery Contact lens Ophthalmology Natamycin lcsh:Ophthalmology lcsh:RE1-994 medicine Clinical Study otorhinolaryngologic diseases business Corneal disease medicine.drug |
| Zdroj: | Journal of Ophthalmology, Vol 2014 (2014) Journal of Ophthalmology |
| ISSN: | 2090-0058 |
| Popis: | Purpose.Alternariaspp. are an uncommon cause of mycotic keratitis. Previous studies onAlternariakeratitis have generally been limited to case reports. We examined the clinical characteristics ofAlternariakeratitis in this study.Methods.The characteristics and outcomes of 7 patients with culture-provenAlternariakeratitis treated in our hospital were compared with 25 previously reported cases.Results.The risk factors forAlternariakeratitis were trauma in 5 patients and soft contact lenses in 1 patient. Six patients with early diagnosis (Alternariakeratitis(n=32), 14 (44%) infections followed trauma, 10 (31%) were associated with preexisting corneal disease or previous ocular surgery, and 5 (16%) occurred in soft contact lens wearers. Successful medical treatment was achieved in 23 (72%) patients, including 10 out of 21 eyes (48%) treated with natamycin and/or amphotericin B. Therapeutic penetrating keratoplasty was performed in 9 (28%) cases.Conclusions.Alternariakeratitis is generally associated with specific risk factors and responds to medical treatment when early diagnosis is performed and prompt antifungal treatment is initiated. |
| Databáze: | OpenAIRE |
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