Membrane Homeostasis Requires Intact pst in Extraintestinal Pathogenic Escherichia coli
| Autor: | Josée Harel, Martin G. Lamarche |
|---|---|
| Rok vydání: | 2009 |
| Předmět: |
Cell Membrane Permeability
Mutant Gene Dosage Virulence Biology medicine.disease_cause Applied Microbiology and Biotechnology Microbiology Cell membrane Escherichia coli medicine Homeostasis Phosphate Transport Proteins Mutation Extraintestinal Pathogenic Escherichia coli Escherichia coli Proteins Cell Membrane Fatty Acids fungi food and beverages Transporter General Medicine medicine.anatomical_structure Bacterial outer membrane |
| Zdroj: | Current Microbiology. 60:356-359 |
| ISSN: | 1432-0991 0343-8651 |
| DOI: | 10.1007/s00284-009-9549-x |
| Popis: | In extraintestinal pathogenic Escherichia coli (ExPEC) strains, mutation in the PstSCAB inorganic phosphate transporter results in multiple sensitivity phenotypes and loss of virulence. Here, we show that a pst mutant is subject to an increased outer membrane permeability and that pst copy number influences fatty acids regulation. Such perturbations are likely to participate in the impaired response of pst mutants to their environment. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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