Reduction of sterigmatocystin biosynthesis and growth of food-borne fungi by lactic acid
| Autor: | Miloš Radosavljević, Gordana Dimić, Ljiljana Mojović, Aleksandra Đukić-Vuković, Sunčica Kocić-Tanackov, Slobodanka Stanojević-Nikolić, Jelena Pejin, Dragana Mladenović |
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| Rok vydání: | 2020 |
| Předmět: |
Immunology
Applied Microbiology and Biotechnology Microbiology 03 medical and health sciences chemistry.chemical_compound Minimum inhibitory concentration 0404 agricultural biotechnology Generally recognized as safe Food science Penicillium aurantiogriseum 2. Zero hunger sterigmatocystin 0303 health sciences Full Paper biology 030306 microbiology Chemistry antifungal activity Aspergillus niger lactic acid Gastroenterology 04 agricultural and veterinary sciences biology.organism_classification 040401 food science Aspergillus parasiticus Aspergillus versicolor fungi Food Science Sterigmatocystin Food contaminant |
| Zdroj: | Bioscience of Microbiota, Food and Health |
| ISSN: | 2186-3342 |
| DOI: | 10.12938/bmfh.2019-029 |
| Popis: | Food contamination by fungi and mycotoxins presents a problem for food safety even today. Since lactic acid (LA) has Generally Recognized As Safe (GRAS) status, the aim of this research was to determine its potential in protection of food against mycological and mycotoxicological contamination. In this study, LA showed an inhibitory effect on the growth of food-borne fungi (Penicillium aurantiogriseum K51, Aspergillus parasiticus KB31, Aspergillus versicolor S72, and Aspergillus niger K95) and on biosynthesis of sterigmatocystin (STE). For the antifungal effect of LA on the growth of food-borne fungi, the disc diffusion and microdilution methods were performed. The effect of LA on the STE biosynthesis by A. versicolor was determined using an LC-MS/MS technique. The largest inhibition zone was observed for A. versicolor (inhibition zone of 24 ± 0.35 mm), while there were no inhibition zones for A. niger and A. parasiticus at all tested LA concentrations. The minimal inhibitory concentration (MIC) of LA on fungi ranged from 25.0 mg/mL to 50.0 mg/mL, while the minimum fungicidal concentrations (MFCs) ranged from 50.0 mg/mL to 100.0 mg/mL. Complete inhibition of STE biosynthesis by A. versicolor was observed at an LA concentration of 50.0 mg/mL. The obtained results showed that LA could be efficient for protection of food against mycological and STE contamination. |
| Databáze: | OpenAIRE |
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