Management of granulomatous common variable immunodeficiency diagnosed in pregnancy: a case report
| Autor: | Peter Kelleher, C Nelson-Piercy, Nichola Cooper, S Wakelin, A L Manson, S Zaheri, S L Seneviratne |
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| Rok vydání: | 2012 |
| Předmět: |
Postnatal Care
Recurrent infections Pediatrics medicine.medical_specialty Gestational Age Third trimester Rare Diseases Pregnancy Placenta medicine Humans biology Cesarean Section business.industry Common variable immunodeficiency Pregnancy Complications Hematologic Infant Newborn Disease Management Obstetrics and Gynecology medicine.disease Combined Modality Therapy Parity Common Variable Immunodeficiency medicine.anatomical_structure Poor antibody response Pediatrics Perinatology and Child Health Childbearing age Immunology biology.protein Drug Therapy Combination Female Antibody business Follow-Up Studies |
| Zdroj: | Journal of Perinatology. 32:387-389 |
| ISSN: | 1476-5543 0743-8346 |
| Popis: | Common variable immunodeficiency (CVID) is a rare condition that affects women of childbearing age with important implications in pregnancy. It is characterised by low immunoglobulins (Igs), poor antibody response and a susceptibility to recurrent infections. The cornerstone of management of CVID is Ig replacement. As the transfer of IgG across the placenta in the third trimester of pregnancy is necessary for protection of the infant in the first months of life, failure to recognise this condition and treat it appropriately can have adverse consequences for the neonate, as well as the mother. Here we describe the complex perinatal medical management of a 34-year-old woman who was diagnosed with CVID in the 26th week of pregnancy. |
| Databáze: | OpenAIRE |
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