Supplementary Tables 1-3, Figures 1-4 from Redirecting T-cell Activity with Anti-BCMA/Anti-CD3 Bispecific Antibodies in Chronic Lymphocytic Leukemia and Other B-cell Lymphomas

Autor: Arnon P. Kater, Raluca Verona, Carel J.M. van Noesel, Eric Eldering, Homer C. Adams, Niels W.C.J. van de Donk, Christie P.M. Verkleij, Marcel Spaargaren, Koen de Heer, Lotte W.H.G. van Mil, An Ngo, Fleur S. Peters, Renate de Boer, Joanne M. Rietveld, Anne W.J. Martens
Rok vydání: 2023
Popis: Supplementary Table 1. CLL Patient characteristics. Supplementary Table 2. Healthy donor characteristics. Supplementary Table 3. MM patient characteristics. Supplementary Figure 1. γ-secretase inhibition increases BCMA levels but does not affect viability of B-cell malignancy cell lines. Supplementary Figure 2. γ-secretase inhibition does not affect viability CLL cells. Supplementary Figure 3. BCMAxCD3 DuoBody® induces activation, degranulation, and cytokine secretion by T cells in the presence of B cell malignancy cell lines. Supplementary Figure 4. BCMAxCD3 DuoBody® induces autologous killing of MM cells.
Databáze: OpenAIRE