Lymph node metastases in carcinoma of the cervix uteri: response to neoadjuvant chemotherapy and its impact on survival
| Autor: | Nidia Gomez Rueda, Susana Vighi, Antonio G. Maya, C. Sananes, Maria L. Bastardas, J Sardi, A. Giaroli, L. Snaidas, Guillermo di Paola |
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| Rok vydání: | 1990 |
| Předmět: |
Oncology
medicine.medical_specialty medicine.medical_treatment Uterine Cervical Neoplasms Vinblastine Metastasis Bleomycin Internal medicine Antineoplastic Combined Chemotherapy Protocols medicine Carcinoma Humans Stage (cooking) Survival rate Cervix Lymph node Chemotherapy business.industry Incidence (epidemiology) Obstetrics and Gynecology medicine.disease Prognosis Survival Rate medicine.anatomical_structure Lymphatic Metastasis Female Radiology Cisplatin business |
| Zdroj: | Gynecologic oncology. 39(1) |
| ISSN: | 0090-8258 |
| Popis: | One hundred and sixty-nine patients with squamous cancer of the cervix uteri treated with three courses of neoadjuvant chemotherapy with the modified VBP scheme are presented. All were subjected to a Wertheim-Meigs operation with paraaortic lymph-adenectomy. The incidence of lymph node metastases is analyzed according to clinical stage, tumor volume, residual tumor in the surgical specimen, and clinical response to neoadjuvant chemotherapy. A significant decrease in the incidence of lymph node involvement was observed in good responders. Survival rates, after 2 years of follow-up, improved in those cases with small residual tumor, negative parametria, and negative nodes. |
| Databáze: | OpenAIRE |
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