Uptake of antiretroviral treatment and viral suppression among men who have sex with men and transgender women in sub-Saharan Africa in an observational cohort study: HPTN 075
| Autor: | Vanessa Cummings, Karen Dominguez, Ravindre Panchia, Theodorus G. M. Sandfort, Philip J. Palumbo, Arthur Ogendo, Autumn Breaud, Noel Kayange, Ying Q. Chen, Yinfeng Zhang, Susan H. Eshleman, Erica L. Hamilton, William Clarke, Mariya V. Sivay, Xu Guo |
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| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
0301 basic medicine
Male HIV Infections Drug resistance Men who have sex with men Cohort Studies Sexual and Gender Minorities 0302 clinical medicine Risk Factors Medicine Mass Screening 030212 general & internal medicine media_common education.field_of_study Sub-Saharan Africa virus diseases General Medicine Viral Load Infectious Diseases Treatment Outcome Cohort Female Viral load HIV drug resistance Cohort study Microbiology (medical) Drug medicine.medical_specialty Anti-HIV Agents media_common.quotation_subject 030106 microbiology Population Transgender Persons Article lcsh:Infectious and parasitic diseases 03 medical and health sciences Internal medicine Drug Resistance Viral Humans lcsh:RC109-216 Transgender women Homosexuality Male education Africa South of the Sahara business.industry HIV Viral suppression Antiretroviral drugs business Follow-Up Studies |
| Zdroj: | International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases International Journal of Infectious Diseases, Vol 104, Iss, Pp 465-470 (2021) |
| ISSN: | 1878-3511 1201-9712 |
| Popis: | Objectives: HPTN 075 enrolled men who have sex with men (MSM) and transgender women (TGW) in sub-Saharan Africa. Persons in HIV care or on antiretroviral treatment (ART) were not eligible to enroll. We evaluated antiretroviral (ARV) drug use, viral suppression, and drug resistance in this cohort over a 12-month follow-up period. Methods: Assessments included 64 participants with HIV (39 MSM, 24 TGW, and one gender not specified). ARV drugs were detected using a qualitative assay. Viral load (VL) and drug resistance testing were performed using commercial assays. Results: Over 12 months, the proportion of participants using ARV drugs increased from 28.1% to 59.4% and the proportion with VLs |
| Databáze: | OpenAIRE |
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