Effectiveness, Safety and Tolerance of Methotrexate in Vietnamese Psoriatic Arthritis Patients
| Autor: | Aleksandra Vojvodic, Anh Tran Ngoc, Quyet Tran Dang, Khang Tran Hau, Torello Lotti, Nghi Dinh Huu, Diep Le Ngoc, Marco Gandolfi, Phuong Pham Thi Minh, Van Bui Thi, Em Dang Van, Francesca Satolli, My Le Huyen, Hien Do Thi Thu, Claudio Feliciani, Vinh Ngo Minh, Michael Tirant, Thuong Nguyen Van |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
medicine.medical_specialty
Treatment response Nausea lcsh:Medicine 030209 endocrinology & metabolism Gastroenterology Disease activity 03 medical and health sciences Psoriatic arthritis 0302 clinical medicine Psoriatic arthritis (PsA) Internal medicine medicine 030212 general & internal medicine Disease activity score (DAS) business.industry lcsh:R Complete remission General Medicine Clinical Science medicine.disease Vomiting Methotrexate medicine.symptom Skin lesion business medicine.drug |
| Zdroj: | Open Access Macedonian Journal of Medical Sciences Open Access Macedonian Journal of Medical Sciences; Vol 7 No 2 (2019): Jan 30 (OAMJMS) Vietnamese Dermatology; 250-252 Open Access Macedonian Journal of Medical Sciences, Vol 7, Iss 2 (2019) |
| ISSN: | 1857-9655 |
| Popis: | AIM: To access the effectiveness, safety and tolerance of methotrexate (MTX) in psoriatic arthritis (PsA) treatment. METHODS: We recruit 37 patients, admitted at HCMC Hospital of Dermato-Venereology from 1/2016 to 3/2017, with MTX dosage ranging from 10 mg to 15 mg per week. RESULTS: Skin lesion response after 12 weeks improved PASI 50: 40.5%, PASI 75: 24.3%. Disease activity score decreased after 12 weeks with ∆DAS28 = -1.43 + 0.79, 37.8% PsA achieved complete remission. Nausea and vomiting were 8.1%. These symptoms were mild and transient. We did not stop MTX usage. The rate of elevating SGPT 2-3 times as much as the upper limit of the normal range was 2.7%. CONCLUSION: We finally demonstrated that the rate of treatment response in Vietnam is the same as demonstrated by foreign authors in other countries. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|