Clinical Usefulness of Magnetic Resonance Imaging in Four Children With Scleroderma
| Autor: | Hisashi Kawashima, Yasuyo Kashiwagi, Hiroko Hara, Atsushi Kumada, Kazushi Agata |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
Flexion contracture
medicine.medical_specialty integumentary system medicine.diagnostic_test business.industry Osteomyelitis Magnetic resonance imaging medicine.disease Article Scleroderma 030218 nuclear medicine & medical imaging 030207 dermatology & venereal diseases 03 medical and health sciences 0302 clinical medicine medicine.anatomical_structure Rheumatology Blood chemistry medicine Methotrexate Bone marrow Radiology Localized Scleroderma business medicine.drug |
| Zdroj: | Archives of Rheumatology. 33:230-235 |
| ISSN: | 2618-6500 2148-5046 |
| Popis: | Children with localized scleroderma may have more serious sequelae than adults with the disease. In this case report, we analyzed four girls with localized scleroderma (generalized morphea) to evaluate the clinical usefulness of magnetic resonance imaging in facilitating disease control and investigating patient responsiveness to various treatments. Two of the children had flexion contracture, and two displayed a clear high-intensity area in the bone marrow under the sclerotic skin on magnetic resonance imaging. Two girls had different bilateral circumferences of the legs or forearms. These abnormalities were detected without any obvious changes in blood chemistry. Our results demonstrated that magnetic resonance imaging is useful for the evaluation of treatment effects for localized scleroderma in children. |
| Databáze: | OpenAIRE |
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