Dance Intervention Impact on Brain Plasticity: A Randomized 6-Month fMRI Study in Non-expert Older Adults
| Autor: | Irena Rektorová, Radek Mareček, Roman Grmela, Zuzana Balazova, Lubos Brabenec, Nela Nemcova-Elfmarkova, Lubomira Novakova, Sylvie Kropacova, Pavlína Vaculíková, Lenka Svobodová |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Aging
medicine.medical_specialty intra-network connectivity Dance Cognitive Neuroscience dance intervention resting state fMRI Neurosciences. Biological psychiatry. Neuropsychiatry Physical exercise Audiology cognitive 03 medical and health sciences 0302 clinical medicine Neuroplasticity medicine Association (psychology) Default mode network 030304 developmental biology 0303 health sciences Resting state fMRI Cognition Brief Research Report attention independent component analysis Analysis of variance Psychology 030217 neurology & neurosurgery RC321-571 Neuroscience |
| Zdroj: | Frontiers in Aging Neuroscience Frontiers in Aging Neuroscience, Vol 13 (2021) |
| ISSN: | 1663-4365 |
| Popis: | Background: Dance is a complex activity combining physical exercise with cognitive, social, and artistic stimulation.Objectives: We aimed to assess the effects of dance intervention (DI) on intra and inter-network resting-state functional connectivity (rs-FC) and its association to cognitive changes in a group of non-demented elderly participants.Methods: Participants were randomly assigned into two groups: DI and life as usual (LAU). Six-month-long DI consisted of supervised 60 min lessons three times per week. Resting-state fMRI data were processed using independent component analysis to evaluate the intra and inter-network connectivity of large-scale brain networks. Interaction between group (DI, LAU) and visit (baseline, follow-up) was assessed using ANOVA, and DI-induced changes in rs-FC were correlated with cognitive outcomes.Results: Data were analyzed in 68 participants (DI; n = 36 and LAU; n = 32). A significant behavioral effect was found in the attention domain, with Z scores increasing in the DI group and decreasing in the LAU group (p = 0.017). The DI as compared to LAU led to a significant rs-FC increase of the default mode network (DMN) and specific inter-network pairings, including insulo-opercular and right frontoparietal/frontoparietal control networks (p = 0.019 and p = 0.023), visual and language/DMN networks (p = 0.012 and p = 0.015), and cerebellar and visual/language networks (p = 0.015 and p = 0.003). The crosstalk of the insulo-opercular and right frontoparietal networks were associated with attention/executive domain Z-scores (R = 0.401, p = 0.015, and R = 0.412, p = 0.012).Conclusion: The DI led to intervention-specific complex brain plasticity changes that were of cognitive relevance. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|