Identification of New Members of a Carbohydrate Kinase-Encoding Gene Family
| Autor: | Edward R. B. McCabe, Steven S. Chua, Kim C. Worley, Randall F. Smith, K.Y. King |
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| Rok vydání: | 1995 |
| Předmět: |
Databases
Factual Molecular Sequence Data Carbohydrates Biology Glycerol Kinase Glucokinase Genetics Animals Humans Gene family Amino Acid Sequence Caenorhabditis elegans Molecular Biology Conserved Sequence Genes Helminth Phylogeny Sequence (medicine) Sequence Homology Amino Acid Sequence database Kinase Carbohydrate Phosphotransferases (Alcohol Group Acceptor) Computational Mathematics Computational Theory and Mathematics Multigene Family Modeling and Simulation Identification (biology) Sequence Alignment Software |
| Zdroj: | Journal of Computational Biology. 2:451-458 |
| ISSN: | 1557-8666 1066-5277 |
| DOI: | 10.1089/cmb.1995.2.451 |
| Popis: | In a sequence database search using the human glycerol kinase-encoding sequence (HUMGLYKINB) as a query, we identified six previously unidentified carbohydrate kinase sequences. Five of the six newly identified sequences appear to be known types of carbohydrate kinases, four are glycerol kinases and one is a gluconokinase. The sixth newly identified sequence, the Caenorhabditis elegans gene, CER08D7.7-CEF59B2.1, shows similarity to the family of carbohydrate kinases including other glycerol kinases, xylulokinases, gluconokinases, ribulokinases, rhamnulokinases, and fucokinases. A phylogenetic comparison of this newly identified Caenorhabditis elegans gene with the other members of the carbohydrate kinase family demonstrated that this sequence cannot be assigned to one of the known classes of carbohydrate kinases. |
| Databáze: | OpenAIRE |
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