Practical guide to prevention of contrast‐induced acute kidney injury after percutaneous coronary intervention

Autor: Antonio Colombo, Giulia Bugani, Antonio Mangieri, Paolo Cimaglia, Eleonora Gaudenzi, Francesco Gallo, Ilja Gardi, Andrea Fisicaro, Francesco Giannini, Alessandra Laricchia, Francesco Ponticelli
Rok vydání: 2020
Předmět:
Zdroj: Catheterization and Cardiovascular Interventions. 97:443-450
ISSN: 1522-726X
1522-1946
DOI: 10.1002/ccd.28740
Popis: Contrast-induced acute kidney injury (CI-AKI) represents a common but serious complication of percutaneous coronary interventions (PCI)-and in general of all those examinations requiring iodinated contrast injection-which affects not only renal function but also long-term prognosis. While several prophylactic approaches were designed in order to prevent CI-AKI, most failed to demonstrate clear benefits in randomized trials, and their implementation is therefore discouraged in clinical practice. The most notorious examples include pre-procedural bicarbonate or N-acetylcysteine, and preprocedural withdrawal of ACE inhibitors/Angiotensin receptor blockers. Those strategies that were instead demonstrated effective include the appropriate use of preprocedural hydration, reduction in contrast volume utilization, adoption of techniques for zero- or ultra-low-contrast procedures, and pharmacological treatments with statins. In this brief review, we summarize the main preventive strategies into brief and pragmatic recommendations designed to improve everyday clinical practice.
Databáze: OpenAIRE