Dysautonomia after traumatic brain injury: a forgotten syndrome?
| Autor: | Lauren D. Wade, Jenelle Crooks, Joseph A Gurka, Jodie L Nicholls, Kim L Felmingham, Ian J. Baguley |
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| Rok vydání: | 1999 |
| Předmět: |
Adult
Male congenital hereditary and neonatal diseases and abnormalities Pediatrics medicine.medical_specialty Time Factors Adolescent Traumatic brain injury medicine.medical_treatment Intensive care medicine Humans Child Paroxysmal sympathetic hyperactivity Retrospective Studies Rehabilitation business.industry Diffuse axonal injury Glasgow Coma Scale Dysautonomia Syndrome Prognosis medicine.disease Functional Independence Measure Surgery Psychiatry and Mental health Autonomic Nervous System Diseases Brain Injuries Papers Female Neurology (clinical) medicine.symptom business |
| Zdroj: | Journal of Neurology, Neurosurgery & Psychiatry. 67:39-43 |
| ISSN: | 0022-3050 |
| DOI: | 10.1136/jnnp.67.1.39 |
| Popis: | OBJECTIVES To better establish the clinical features, natural history, clinical management, and rehabilitation implications of dysautonomia after traumatic brain injury, and to highlight difficulties with previous nomenclature. METHODS Retrospective file review on 35 patients with dysautonomia and 35 sex and Glasgow coma scale score matched controls. Groups were compared on injury details, CT findings, physiological indices, and evidence of infections over the first 28 days after injury, clinical progress, and rehabilitation outcome. RESULTS the dysautonomia group were significantly worse than the control group on all variables studied except duration of stay in intensive care, the rate of clinically significant infections found, and changes in functional independence measure (FIM) scores. CONCLUSIONS Dysautonomia is a distinct clinical syndrome, associated with severe diffuse axonal injury and preadmission hypoxia. It is associated with a poorer functional outcome; however, both the controls and patients with dysautonomia show a similar magnitude of improvement as measured by changes in FIM scores. It is argued that delayed recognition and treatment of dysautonomia results in a preventable increase in morbidity. |
| Databáze: | OpenAIRE |
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