Acute heart failure in multisystem inflammatory syndrome in children (MIS-C) in the context of global SARS-CoV-2 pandemi
| Autor: | Fanny Bajolle, Diala Khraiche, Caroline Ovaert, Sylvie Falcon-Eicher, Maëlle Selegny, Antoine Legendre, Zahra Belhadjer, Mehdi Oualha, Laurent Bonnemains, Samya Abakka, Sébastien Hascoët, Sylvain Renolleau, Lucile Houyel, Pierre Mauran, Nathan Giroux, Alice Maltret, Gilles Bosser, Sylvie Di Filippo, Bruno Lefort, Julie Wacker, Sophie Malekzadeh-Milani, Pamela Moceri, Damien Bonnet, Jean-Benoit Thambo, Mathilde Meot, Marion Grimaud, Jeanne Bordet, Maurice Beghetti, Johanne Auriau |
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| Přispěvatelé: | Pathologies Pulmonaires et Plasticité Cellulaire - UMR-S 1250 (P3CELL), Université de Reims Champagne-Ardenne (URCA)-Institut National de la Santé et de la Recherche Médicale (INSERM) |
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Pediatrics
medicine.medical_specialty Myocarditis Ejection fraction business.industry Cardiogenic shock [SDV]Life Sciences [q-bio] Context (language use) 030204 cardiovascular system & hematology Overweight medicine.disease 3. Good health 03 medical and health sciences 0302 clinical medicine Intensive care Heart failure Co 2 Medicine 030212 general & internal medicine medicine.symptom Cardiology and Cardiovascular Medicine business ComputingMilieux_MISCELLANEOUS Asthma |
| Zdroj: | Archives of Cardiovascular Diseases Supplements Archives of Cardiovascular Diseases Supplements, Elsevier/French Society of Cardiology, 2021, 13 (4), pp.271. ⟨10.1016/j.acvdsp.2021.06.005⟩ Archives of Cardiovascular Diseases. Supplements |
| ISSN: | 1878-6480 |
| DOI: | 10.1016/j.acvdsp.2021.06.005⟩ |
| Popis: | Background Cardiac injury and myocarditis have been described in adults with coronavirus disease 2019 (COVID-19). Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in children is typically minimally symptomatic. We report a series of febrile pediatric patients with acute heart failure potentially associated with SARS-CoV-2 infection and the multisystem inflammatory syndrome in children as defined by the US Centers for Disease Control and Prevention. Methods Over a 2-month period, contemporary with the SARS-CoV-2 pandemic in France and Switzerland, we retrospectively collected clinical, biological, therapeutic, and early outcomes data in children who were admitted to pediatric intensive care units in 14 centers for cardiogenic shock, left ventricular dysfunction, and severe inflammatory state. Results Thirty-five children were identified and included in the study. Median age at admission was 10 years (range, 2–16 years). Comorbidities were present in 28%, including asthma and overweight. Gastrointestinal symptoms were prominent. Left ventricular ejection fraction was |
| Databáze: | OpenAIRE |
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