Additional file 1 of Location matters: highly divergent protein levels in samples from different CNS compartments in a clinical trial of rituximab for progressive MS

Autor: Bergman, Joakim, Svenningsson, Anders, Liv, Per, Bergenheim, Tommy, Burman, Joachim
Rok vydání: 2020
DOI: 10.6084/m9.figshare.12737196.v1
Popis: Additional file 1: Figure S1. Proximity Extension Assay (PEA). (A) a matched pair of antibodies linked to unique oligonucleotides are added for each protein of interest. (B) When bound to a protein, the paired oligonucleotides come in close vicinity of each other and hybridize, which enables a DNA amplification by the addition of a DNA polymerase. (C) The DNA amplification is detected and quantified by quantitative real-time PCR. Picture provided by Olink Proteomics.
Databáze: OpenAIRE