| Autor: |
Savitri Aninditha, Nandula, Chinmayi Sree, Boddepalli, Sai Dheeraj, Gutlapalli, Vamsi Krishna, Lavu, Rana, Abdelwahab Mohamed Abdelwahab, Ruimin, Huang, Shanthi, Potla, Sushen, Bhalla, Yousif, AlQabandi, Prachi, Balani |
| Rok vydání: |
2022 |
| Předmět: |
|
| Zdroj: |
Cureus. |
| ISSN: |
2168-8184 |
| Popis: |
A frequent complication in kidney transplantation is post-transplant diabetes mellitus (PTDM). The primary goal of this study is to review the risk factors and preventive methods and compare the different available anti-diabetic medications for the management of PTDM. We searched databases like Pubmed and Google Scholar for related articles using specific terms and phrases. Following a thorough investigation, we applied the inclusion and exclusion criteria and completed a quality assessment. Modifiable risk factors have a significant role in the development of PTDM. The combinations of immunosuppressive treatment tacrolimus (TAC), cyclosporine A (CYC), and everolimus (EVL), steroids increase the incidence of PTDM significantly. Insulin is the most effective treatment for PTDM in the early transplant period; however, oral anti-diabetic medications look promising. Further clinical trials are required to determine the optimum treatment method for reducing the occurrence of PTDM and treating the existing condition with novel anti-hyperglycemic medications. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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