Iron status in late pregnancy is inversely associated with birth weight in Colombia
| Autor: | Rossana López-Sáleme, Francisco Edna-Estrada, N Alvis-Zakzuk, Alejandra Puerto, Annabelle Trojan, Alvaro Alvarez, Nelson Alvis-Guzman, Josefina Zakzuk |
|---|---|
| Jazyk: | Spanish; Castilian |
| Rok vydání: | 2021 |
| Předmět: |
0301 basic medicine
medicine.medical_specialty Birth weight Iron Medicine (miscellaneous) Anaemia Prenatal care Colombia Cohort Studies 03 medical and health sciences 0302 clinical medicine Risk Factors Pregnancy Medicine Birth Weight Humans Birth outcomes 030212 general & internal medicine Prospective Studies 030109 nutrition & dietetics Nutrition and Dietetics business.industry Obstetrics Iron deficiency Iron status Public Health Environmental and Occupational Health Infant Newborn Pregnancy Outcome medicine.disease Late pregnancy Low birth weight Gestation Small for gestational age Premature Birth Female medicine.symptom business |
| Zdroj: | REDICUC-Repositorio CUC Corporación Universidad de la Costa instacron:Corporación Universidad de la Costa |
| ISSN: | 1368-9800 |
| Popis: | Objective:Gestational anaemia (GA) is common in developing countries. This study assessed the relationship of late GA and negative perinatal outcomes in participants recruited in a reference maternity unit of the Caribbean region of Colombia.Design:Prospective analytical birth cohort study. Maternal Hb and serum ferritin (SF) levels were measured. GA was defined as Hb levels Setting:Mothers in the first stage of labour, living in urban or rural areas of Bolívar, were enrolled in an obstetrical centre located in Cartagena, Colombia. Blood and stool samples were taken prior delivery. Maternal blood count, SF levels and infant anthropometric data were recorded for analysis.Participants:1218 pregnant women aged 18–42 years and their newborns.Results:Prevalence of GA and SF depletion was 41·6 % and 41·1 %, respectively. GA was positively associated with poverty-related sociodemographic conditions. Prenatal care attendance lowered the risk of PB, LBW and SGA. Birth weight was inversely associated with Hb levels, observing a −36·8 g decrease in newborn weight per 0·62 mmol/l (or 1 g/dl) of maternal Hb. SF depletion, but not anaemia, was associated with PB. SGA outcome showed a significant association with anaemia, but not a significant relationship with SF depletion.Conclusions:Birth weight and other-related perinatal outcomes are negatively associated with Hb and SF depletion. Prenatal care attendance reduced the risk of negative birth outcomes. |
| Databáze: | OpenAIRE |
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