Early use of continuous glucose monitoring in children and adolescents after total pancreatectomy with islet autotransplantation
| Autor: | Neha Potlapalli, Varvara A. Kirchner, Kendall R. McEachron, Melena D. Bellin, Sarah Jane Schwarzenberg, Arpana Rayannavar, Gregory J. Beilman, Srinath Chinnakotla, Elissa M. Downs |
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| Rok vydání: | 2020 |
| Předmět: |
Male
Pediatrics medicine.medical_specialty endocrine system diseases Adolescent Total pancreatectomy Endocrinology Diabetes and Metabolism medicine.medical_treatment Islets of Langerhans Transplantation 030209 endocrinology & metabolism Pilot Projects Glycemic Control Transplantation Autologous 03 medical and health sciences 0302 clinical medicine Pancreatectomy Diabetes management Pancreatitis Chronic Internal Medicine medicine Humans 030212 general & internal medicine Child Glycemic geography geography.geographical_feature_category Continuous glucose monitoring business.industry Insulin Blood Glucose Self-Monitoring nutritional and metabolic diseases Islet medicine.disease Autotransplantation Patient Satisfaction Pediatrics Perinatology and Child Health Pancreatitis Feasibility Studies Female business |
| Zdroj: | Pediatric diabetesREFERENCES. 22(3) |
| ISSN: | 1399-5448 |
| Popis: | Background Children undergoing total pancreatectomy with islet autotransplantation (TPIAT) for chronic pancreatitis require intensive insulin therapy early after TPIAT with narrow glycemic targets, which can a present significant care burden. Outpatient use of continuous glucose monitoring (CGM) systems by children and caregivers early after TPIAT is inadequately studied. Methods In this open-label study, we randomized 14 children and adolescents (mean age 15.4 years) after hospital discharge for TPIAT to Dexcom G6 CGM (n = 7) or standard care with a glucometer (n = 7) to assess acceptability and glycemic control with use of CGM versus usual care (glucometer). Participants in the control arm also wore a blinded CGM for 1 week. Result Children randomized to real-time CGM had lower mean sensor glucose values compared with controls (p = 0.002), and high overall satisfaction with CGM. Conclusions Our data indicate that CGM is a useful adjunct to diabetes management for children who have recently undergone TPIAT. |
| Databáze: | OpenAIRE |
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