Recurrent Interstitial Pneumonitis and Pulmonary Hemorrhage Secondary to Amiodarone Toxicity

Autor: Victor Salloum, Joe J Lin, Rami Jambeih
Rok vydání: 2010
Předmět:
Zdroj: Kansas Journal of Medicine. 3:15-18
ISSN: 1948-2035
DOI: 10.17161/kjm.v3i5.11324
Popis: Introduction Amiodarone is a commonly used drug for the treatment of cardiac arrhythmias. It has a broad range of toxicity including photosensitivity, blue-gray discoloration of the skin, thyroid dysfunction, corneal deposits, abnormal liver function tests, and bone marrow suppression. 1 Pulmonary toxicity is the most serious adverse effect of amiodarone. Treatment of amiodaroneinduced pulmonary toxicity includes discontinuation of the drug and initiation of glucocorticoid therapy in the majority of symptomatic patients. This case of recurrent amiodarone toxicity was manifested by acute interstitial pneumonitis and diffuse alveolar hemorrhage after a rapid taper of glucocorticoids.
Databáze: OpenAIRE