952-29 Long-term Follow-up of Surgical Repair of Ostium Primum Defects in Adults
| Autor: | Nancy M. Kinchla, John J. Collins, Michael J. Landzberg, Keith A. Horvath, Pamela Hyde, Redmond P. Burke, Lawrence H. Cohn |
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| Rok vydání: | 1995 |
| Předmět: |
medicine.medical_specialty
Mitral regurgitation business.industry medicine.medical_treatment Mitral valve replacement Atrial fibrillation macromolecular substances Primary interatrial foramen medicine.disease Atrial septal defects Surgery medicine.anatomical_structure Internal medicine medicine.artery Pulmonary artery cardiovascular system medicine Cardiology Vascular resistance cardiovascular diseases Myocardial infarction Cardiology and Cardiovascular Medicine business |
| Zdroj: | Journal of the American College of Cardiology. 25:199A |
| ISSN: | 0735-1097 |
| DOI: | 10.1016/0735-1097(95)92286-e |
| Popis: | The natural history of patients (pts) undergoing surgical repair of ostium primum atrial septal defects (ASD-1) in adulthood remains unclear. We followed 33 pts who underwent surgical correction of ASD-l at our institution at ages 20–73 years (mean = 42), 12 of these patients were over the age of 50 at the time of surgery. Moderate preoperative exercise incapacity (NYHA Class g2) was present in 4 pts, and 6 were in atrial fibrillation. Preoperative mean pulmonary artery pressure g25 mmHg, pulmonary vascular resistance g4 Wood units, or moderate-severe mitral regurgitation was present in 8, 4, and 5 pts, respectively, Autologous pericardium was used to patch the ASD-l in 30 pts (91 %). Mitral valvuloplasty, consisting of cleft repair (n = 10) and mitral valve replacement (n = 2), were performed selectively. At a mean follow-up of 5.3 years (1 month-18.2 years), all 28 surviving pts are free of exercise limitation (NYHA Class 1). Late post-operative deaths have occurred in 5 pts (15%); related to myocardial infarction, stroke, hepatic failure, renal failure, or sepsis. Reoperation was required in 2 pts (6%); for a residual ASD-1 (n = 1). and severe mitral regurgitation (n = 1), both within the first postoperative year. The presence of advanced age at operation, symptoms, atrial arrhythmias, mitral regurgitation, or moderately increased pulmonary vascular resistance did not predict late postoperative mortality, complications or functional capacity. Conclusion ASD-1 can be repaired in adult pts with the expectation of excellent long-term results, independent of age at operation and preoperative mitral valve function; and despite the presence of atrial fibrillation, or moderately elevated pulmonary vascular resistance. |
| Databáze: | OpenAIRE |
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