Contrasting Sleeve Gastrectomy with Lifestyle Modification Therapy in the Treatment of Polycystic Ovary Syndrome
| Autor: | Yanting Xie, Aiguo Lu, Zhuqing Zhou, Xiaoqi Yin, Yunqing Zhi, Zhe Zhu, Qixin Jiang, Kaijing Wang |
|---|---|
| Rok vydání: | 2015 |
| Předmět: |
Adult
medicine.medical_specialty Sleeve gastrectomy medicine.drug_class medicine.medical_treatment media_common.quotation_subject Urology Body Mass Index Menstruation Young Adult Weight loss Gastrectomy Weight Loss medicine Humans Ovulation Life Style hirsutism media_common Gynecology Cognitive Behavioral Therapy business.industry Androgen medicine.disease Polycystic ovary Surgery Obesity Morbid Treatment Outcome Female medicine.symptom business Body mass index Polycystic Ovary Syndrome |
| Zdroj: | Journal of laparoendoscopicadvanced surgical techniques. Part A. 25(6) |
| ISSN: | 1557-9034 |
| Popis: | To explore the feasibility of sleeve gastrectomy (SG) as a treatment for polycystic ovary syndrome (PCOS) and its potential to improve clinical efficacy in PCOS patients with symptoms of oligomenorrhea.Twenty-four obese patients with PCOS underwent laparoscopic SG. Simultaneously, 24 obese patients with PCOS received lifestyle modification therapy (LMT). Follow-ups were conducted at 3-6 months. Weight loss, menstruation, and improvements in hirsutism and metabolic symptoms were compared.In the SG group, 20 patients were restored to normal menstrual cycles and ovulation at 3-6 months after surgery. Their average androgen levels decreased significantly following surgery (P=.012). Conversely, only 6 patients in the LMT group were restored to normal menstrual cycles and ovulation after receiving 3 months of treatment. Their average preoperative and postoperative androgen levels showed a nonstatistically significant decrease (P.05). Compared with the LMT group, the SG group showed more pronounced improvements in menstruation. Additionally, body mass and body mass index were significantly reduced in patients in the SG group 3 months after the surgeries, with maximum weight loss observed at approximately 6 months after surgery. Patients who received LMT showed a gradual weight reduction such that body mass decreased significantly after 3 months (P. 001). Compared with patients in the LMT group, patients in the SG group showed greater weight loss results (P.0001).In patients with PCOS, SG resulted in more marked weight loss and better improvements in clinical symptoms compared with LMT. |
| Databáze: | OpenAIRE |
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