Staging performance of whole-body DWI, PET/CT and PET/MRI in invasive ductal carcinoma of the breast
| Autor: | Marco Salvatore, Ciprian Catana, Mark Vangel, Angelo Luongo, Carlo Iannace, Bruce R. Rosen, Mazzeo Filomena, Alberto Signore, Luigi Mansi, Umar Mahmood, Onofrio A. Catalano, Andrea Soricelli, Marco Catalano, Niccolo Fuin, Dania Daye |
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| Rok vydání: | 2017 |
| Předmět: |
Adult
Cancer Research medicine.medical_specialty diffusion-weighted imaging Breast Neoplasms carcinoma breast cancer pet/ct pet/mr staging adult aged breast neoplasms carcinoma ductal breast diffusion magnetic resonance imaging female fluorodeoxyglucose f18 humans magnetic resonance imaging middle aged neoplasm staging positron emission tomography computed tomography radiopharmaceuticals retrospective studies young adult 030218 nuclear medicine & medical imaging Young Adult 03 medical and health sciences Prostate cancer 0302 clinical medicine Breast cancer McNemar's test Fluorodeoxyglucose F18 Positron Emission Tomography Computed Tomography Humans Medicine breast Aged Neoplasm Staging Retrospective Studies PET-CT medicine.diagnostic_test business.industry Carcinoma Ductal Breast Cancer Magnetic resonance imaging Middle Aged medicine.disease ductal Magnetic Resonance Imaging Diffusion Magnetic Resonance Imaging Oncology Positron emission tomography 030220 oncology & carcinogenesis Female Radiology Radiopharmaceuticals business Diffusion MRI |
| Zdroj: | International Journal of Oncology. 51:281-288 |
| ISSN: | 1791-2423 1019-6439 |
| DOI: | 10.3892/ijo.2017.4012 |
| Popis: | The aim of the present study was to evaluate the performance of whole-body diffusion-weighted imaging (WB-DWI), whole-body positron emission tomography with computed tomography (WB-PET/CT), and whole-body positron emission tomography with magnetic resonance imaging (WB-PET/MRI) in staging patients with untreated invasive ductal carcinoma of the breast. Fifty-one women with newly diagnosed invasive ductal carcinoma of the breast underwent WB-DWI, WB-PET/CT and WB-PET/MRI before treatment. A radiologist and a nuclear medicine physician reviewed in consensus the images from the three modalities and searched for occurrence, number and location of metastases. Final staging, according to each technique, was compared. Pathology and imaging follow-up were used as the reference. WB-DWI, WB-PET/CT and WB-PET/MRI correctly and concordantly staged 33/51 patients: stage IIA in 7 patients, stage IIB in 8 patients, stage IIIC in 4 patients and stage IV in 14 patients. WB-DWI, WB-PET/CT and WB-PET/MRI incorrectly and concordantly staged 1/51 patient as stage IV instead of IIIA. Discordant staging was reported in 17/51 patients. WB-PET/MRI resulted in improved staging when compared to WB-PET/CT (50 correctly staged on WB-PET/MRI vs. 38 correctly staged on WB-PET/CT; McNemar's test; p |
| Databáze: | OpenAIRE |
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