| Autor: |
Janis M. Taube, Alexander S. Baras, Ludmila Danilova, Evan J. Lipson, Robert A. Anders, Raphael Gottardo, Haiying Xu, Aleksandra Ogurtsova, Farah Succaria, Julie E. Stein, Abha Soni, Peter Nguyen, Benjamin Green, Elizabeth L. Engle, Kara M. Schenk, Deniz Ates, Etienne Becht, Sneha Berry, Nicolas A. Giraldo |
| Rok vydání: |
2023 |
| DOI: |
10.1158/2326-6066.22544504.v1 |
| Popis: |
Supplementary Table S1. Clinicopathologic characteristics of the cohort separated by death at the 5-year time point. Supplementary Table S2. Primary and secondary antibody information and TSA dye pairings for multiplex IF panel. Supplementary Table S3. Twenty highest ranking variables associating with overall survival by univariate Cox regression analysis. Supplementary Table S4. Density and proximity variables selected by least absolute shrinkage and selection operator (LASSO) methods using a 5-fold cross-validation. Supplementary Figure S1. Image cytometry to quantify immune cell biomarkers in metastatic melanoma. Supplementary Figure S2. The expression of PD-L1 on tumor cells and 'Other' cells is determined by their proximity to CD8+ cells. Supplementary Figure S3. Characterization of immune neighborhoods associated with overall survival. Supplementary Computational Methods. Survival and clinical statistical analysis - R markdown document. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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