Hepatitis C Virus Exposure Rate among Health-care Workers in Rural Lower Egypt Governorates
| Autor: | Ashraf Elbahrawy, Hafez Abdelhafeez, Ahmed Elwassief, Ahmed Alashker, Ahmed Eliwa, Khaled Makboul, Mohamed Abdellah Othman, Hossam Shahbah, Abdallah Mahmoud Abdallah, Sadek Mostafa, Mohamed Morsy, Arafat Kasem, Mohamed S. Ali, Mohamed Ali Abdelbaseer |
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| Rok vydání: | 2017 |
| Předmět: |
High rate
medicine.medical_specialty business.industry Hepatitis C virus virus diseases Viremia Mean age Hepatitis C medicine.disease_cause medicine.disease 03 medical and health sciences 0302 clinical medicine Internal medicine Health care Internal Medicine medicine Endocrinology diabetology 030211 gastroenterology & hepatology Original Article 030212 general & internal medicine business Nested polymerase chain reaction |
| Zdroj: | Journal of translational internal medicine. 5(3) |
| ISSN: | 2450-131X |
| Popis: | Background and Objectives Studies on hepatitis C virus (HCV) in Egypt supported a strong role for various exposures in the health-care setting. In this study, we attempted to estimate the frequency of HCV exposure among Egyptian health-care workers (HCWs). Methods Five hundred and sixty-four (564) HCWs were included in this study. Two hundred and fifty-eight (45.74%) were health-care providers and 306 (54.25%) were non-health-care providers. All HCWs completed both the study questionnaire and provided a blood sample for anti-HCV testing by third-generation enzyme-linked immunosorbent assay. Subsequently, anti-HCV-positive samples were tested for HCV RNA using nested polymerase chain reaction (PCR). Results The mean age of included HCWs was 33.0 ± 9.8 years; of them, 319 (56.56%) were males and 245 (43.44%) were females. The mean duration of health-care work was 9.3 ± 6.7 years. The frequency of antibody against hepatitis C virus (anti-HCV) among included HCWs was 8.7% (n = 49). Old age and prolonged duration of health-care work were significantly associated with anti-HCV seropositivity. Forty (81.63%) of 49 with anti-HCV-positive HCWs had positive hepatitis C viremia. The frequency of HCV RNA positivity increased with age. The frequency of eradicated past infection among nurses (36.85%) was markedly higher than that (6.7%) detected in non-health-care providers. Conclusion High rate of HCV infection is detected in Egyptian HCWs in rural Lower Egypt governorates. Health-care providers seem to eradicate HCV infection more frequently than non-health-care providers. National screening and treatment of infected HCWs are recommended. |
| Databáze: | OpenAIRE |
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