Separation, quantification and characterisation of the pigment produced by Paecilomyces lilacinus TD16
Autor: | Ran Yan, Xiangying Xing, Xian-Yong Yu, Qinglin Dong, Kang-Li Shi |
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Rok vydání: | 2021 |
Předmět: | |
Zdroj: | Natural Product Research. 36:5053-5057 |
ISSN: | 1478-6427 1478-6419 |
Popis: | Fungal pigments are important natural products with a wide range of applications. In this study, the purple-red pigment produced by the fungus Paecilomyces lilacinus TD16 (TD16 pigment) was separated with acidulated ethyl acetate and purified by silica gel column chromatography. Results of UV-visible spectrum and HPLC analyses showed that TD16 pigment is a new polyketide pigment with three absorption peaks at 228, 272 and 527 nm and a retention time of 11.4665 min distinct from those of other Paecilomyces-sourced pigments. Results of kinetic analysis and antimicrobial activity assay showed that TD16 pigment is a non-growth-associated secondary products with broad-spectrum antimicrobial activity on both bacteria and fungi and thus of potential application in industry. |
Databáze: | OpenAIRE |
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