Upregulation of Anti-Oxidative Stress Response Improves Metabolic Changes in L-Selectin-Deficient Mice but Does Not Prevent NAFLD Progression or Fecal Microbiota Shifts

Autor: Anshu Babbar, Daniela C. Kroy, Moritz Muschaweck, Thomas Ritz, Hannah K. Drescher, Angela Schippers, Norbert Wagner, Thomas Clavel, Christian Trautwein, Thomas C. A. Hitch, Sreepradha Eswaran
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Male
0301 basic medicine
Adipose tissue
White adipose tissue
Gut flora
medicine.disease_cause
Feces
Mice
0302 clinical medicine
Non-alcoholic Fatty Liver Disease
oxidative stress
Biology (General)
Spectroscopy
Kelch-Like ECH-Associated Protein 1
biology
Fatty liver
General Medicine
western diet
Up-Regulation
Computer Science Applications
Chemistry
Liver
ddc:540
030211 gastroenterology & hepatology
L-selectin
Signal Transduction
medicine.medical_specialty
Keap1
QH301-705.5
NF-E2-Related Factor 2
Article
Catalysis
Nrf2
Inorganic Chemistry
03 medical and health sciences
Immune system
cellular migration
Downregulation and upregulation
Internal medicine
NAFLD
medicine
microbiota
Animals
Physical and Theoretical Chemistry
QD1-999
Molecular Biology
Organic Chemistry
medicine.disease
biology.organism_classification
Gastrointestinal Microbiome
Mice
Inbred C57BL

030104 developmental biology
Endocrinology
Diet
Western

Hepatocytes
biology.protein
Reactive Oxygen Species
Oxidative stress
Zdroj: International Journal of Molecular Sciences
Volume 22
Issue 14
International journal of molecular sciences 22(14), 7314 (2021). doi:10.3390/ijms22147314 special issue: "Molecular Endocrinology and Metabolism / José L. Quiles, Section Editor-in-Chief"
International Journal of Molecular Sciences, Vol 22, Iss 7314, p 7314 (2021)
ISSN: 1422-0067
2214-7314
DOI: 10.3390/ijms22147314
Popis: International journal of molecular sciences 22(14), 7314 (2021). doi:10.3390/ijms22147314 special issue: "Molecular Endocrinology and Metabolism / José L. Quiles, Section Editor-in-Chief"
Published by Molecular Diversity Preservation International, Basel
Databáze: OpenAIRE