Pseudotumoral Presentation of Cerebral Amyloid-Beta Angiopathy: Case Report and Review of Literature
| Autor: | Miguel Saucedo, Pablo Dezanzo, Rafael Torino, Gustavo Sevlever, Fabio Maximiliano Gonzalez, Manuel Fernandez Pardal, Ricardo Reisin, Luciana Leon Cejas, Claudia Uribe Roca, Pablo Bonardo, Lucrecia Bandeo, Marta Ines Bala, Carlos Rugilo, Sol Pacha |
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| Rok vydání: | 2021 |
| Předmět: |
Pediatrics
medicine.medical_specialty Amyloid beta Encephalopathy Pseudotumoral Review Article Disease 030218 nuclear medicine & medical imaging Angiopathy 03 medical and health sciences 0302 clinical medicine medicine Tumor-like Cerebral amyloid angiopathy Cognitive decline Biological Psychiatry biology business.industry medicine.disease Psychiatry and Mental health Radiological weapon biology.protein Neoplasm Presentation (obstetrics) business 030217 neurology & neurosurgery |
| Zdroj: | Psychiatry Investigation |
| ISSN: | 1976-3026 1738-3684 |
| DOI: | 10.30773/pi.2020.0201 |
| Popis: | Objective Cerebral amyloid angiopathy-related inflammation (CAA-RI) is a rare and potentially treatable encephalopathy that usually affects people older than 50 years old and has an acute or subacute clinical presentation characterized by rapidly evolving cognitive decline, focal deficits and seizures. In a small subset of patients the disease can adopt a pseudotumoral form in the neuroimages that represents a very difficult diagnostic challenge.Methods Here in we report a patient with a tumour-like presentation of histopathologically confirmed CAA-RI.Results We also conducted a search and reviewed the clinical and radiological features of 41 cases of pseudotumoral CAA-RI previously reported in the literature in order to identify those characteristics that should raise diagnostic suspicions of the disease, there by avoiding unnecessary surgical treatments.Conclusion The therapy of CAA-RI with steroids is usually effective and clinical and radiological remission can be achieved in the first month in approximately 70% of cases. |
| Databáze: | OpenAIRE |
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