Analysis of SteraMist ionized hydrogen peroxide technology in the sterilization of N95 respirators and other PPE
| Autor: | Mary Carmack, Michael S. Sinha, Heather Manning, David Krikorian, Peter K. Sorger, Florence T. Bourgeois, Enze Tian, Rajiv Gupta, Deborah Plana, Jinhan Mo, Nicole R. LeBoeuf, David G. Turner, Sherry H. Yu, Helen Yang, Ju Li, Avilash Cramer |
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| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
0301 basic medicine
business.product_category Coronavirus disease 2019 (COVID-19) Science 030106 microbiology Economic shortage 030501 epidemiology law.invention 03 medical and health sciences chemistry.chemical_compound law Respirator Hydrogen peroxide Personal protective equipment Filtration Single use Multidisciplinary Waste management Sterilization (microbiology) chemistry Environmental science Medicine 0305 other medical science business |
| Zdroj: | Scientific Reports Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021) |
| ISSN: | 2045-2322 |
| DOI: | 10.1038/s41598-021-81365-7 |
| Popis: | The COVID-19 pandemic has led to widespread shortages of personal protective equipment (PPE) for healthcare workers, including of N95 masks (filtering facepiece respirators; FFRs). These masks are intended for single use but their sterilization and subsequent reuse has the potential to substantially mitigate shortages. Here we investigate PPE sterilization using ionized hydrogen peroxide (iHP), generated by SteraMist equipment (TOMI; Frederick, MD), in a sealed environment chamber. The efficacy of sterilization by iHP was assessed using bacterial spores in biological indicator assemblies. After one or more iHP treatments, five models of N95 masks from three manufacturers were assessed for retention of function based on their ability to form an airtight seal (measured using a quantitative fit test) and filter aerosolized particles. Filtration testing was performed at a university lab and at a National Institute for Occupational Safety and Health (NIOSH) pre-certification laboratory. The data demonstrate that N95 masks sterilized using SteraMist iHP technology retain filtration efficiency up to ten cycles, the maximum number tested to date. A typical iHP environment chamber with a volume of ~ 80 m3 can treat ~ 7000 masks and other items (e.g. other PPE, iPADs), making this an effective approach for a busy medical center. |
| Databáze: | OpenAIRE |
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