Synthesis of highly stable κ/ι-hybrid carrageenan micro- and nanogels via a sonication-assisted microemulsion route
| Autor: | Omar P. Troncoso, Fernando G. Torres, Daniel López, Sol Rodriguez, Junior Arroyo, Karen N. Gonzales |
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| Rok vydání: | 2020 |
| Předmět: |
Polymers and Plastics
Chemistry Sonication 02 engineering and technology Hybrid carrageenan 010402 general chemistry 021001 nanoscience & nanotechnology 01 natural sciences Microemulsion 0104 chemical sciences Carrageenan chemistry.chemical_compound Chemical engineering 0210 nano-technology Micro- and nanogels |
| Zdroj: | Digital.CSIC. Repositorio Institucional del CSIC instname |
| ISSN: | 2045-1377 2041-2479 |
| Popis: | Novel carrageenan micro- and nanogels were developed via a sonication-assisted microemulsion processing route. The diameter of the dry samples ranged 197.3 −421.35 nm whereas the diameter of the samples suspended in water ranged 467.8–605.9 nm. Hybrid κ/ι-carrageenan, rather than κ- or ι-carrageenan was used for the first time for the preparation of micro- and nanogels. KCl was used as a cross-linking agent and Tween 80 was used as surfactant. The micro- and nanogels suspended in water were found to simultaneously exhibit a lower diameter, and a lower swelling ratio with higher Tween 80 content. The micro- and nanogel suspension yields a zeta potential value of −50.5 mV, superior to values reported elsewhere for pure κ- or ι-carrageenan micro- and nanogels. The high stability was attributed to the high hydrophile-lipophile balance (HLB = 15) value of Tween 80. These results suggest that hybrid κ/ι-carrageenan micro- and nanogels are promising candidates for smart therapeutics applications. |
| Databáze: | OpenAIRE |
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