Effects of age and physical fitness on microcirculatory function
| Autor: | Carmela Morizzo, Gino Santoro, Alfredo Quiñones-Galvan, Eleuterio Ferrannini, Fabio Galetta, Valter Lubrano, Ferdinando Franzoni, Carlo Palombo |
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| Jazyk: | angličtina |
| Rok vydání: | 2003 |
| Předmět: |
Adult
Male Aging medicine.medical_specialty Physical fitness Biological Availability Physical exercise Nitric Oxide Running Nitric oxide Microcirculation chemistry.chemical_compound Internal medicine Laser-Doppler Flowmetry medicine Humans Endothelial dysfunction Nitrite Skin Analysis of Variance Foot business.industry VO2 max General Medicine Middle Aged Hand medicine.disease Surgery Endocrinology chemistry Regional Blood Flow Case-Control Studies Physical Endurance Endothelium Vascular Analysis of variance business |
| Popis: | Sedentary aging is associated with endothelial dysfunction and nitric oxide (NO) impairment. The aim of the present study was to assess the effects of regular physical exercise on nitrite/nitrate (NOx) concentrations and microcirculatory function in older men compared with young individuals. We measured NOx plasma concentrations and baseline and stimulated skin blood flow (SBF) by laser Doppler flowmetry in 39 male athletes [range, 22–72 years; maximal oxygen consumption (VO2max), 60.0±4.7 ml·min-1·kg of body weight-1 (mean±S.D.)] and 45 age- and sex-matched sedentary controls (VO2max, 38.0±7.1 ml·min-1·kg of body weight-1). NOx concentrations were higher in athletes than in controls (50.4±16.3 compared with 39.0±15.4 µmol/l; P0.30, P |
| Databáze: | OpenAIRE |
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