CA 15.3, CEA and TPA tumor markers in the early diagnosis of breast cancer relapse
| Autor: | F. Jarque, A. Lluch, E. Vizcarra, R Cibrián, J. García-Conde |
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| Předmět: |
Adult
CA15-3 Oncology Cancer Research medicine.medical_specialty Tissue Polypeptide Antigen CA 15-3 Breast Neoplasms Disease Neoplasm Recurrence Breast cancer Carcinoembryonic antigen Internal medicine Biomarkers Tumor Humans Medicine Neoplasm Metastasis Aged biology business.industry Mucin-1 General Medicine Middle Aged medicine.disease Carcinoembryonic Antigen Clinical evidence biology.protein Female Neoplasm Recurrence Local Peptides business |
| Zdroj: | Europe PubMed Central |
| Popis: | To evaluate the utility of CA 15.3 in detecting breast cancer relapse before clinical evidence of metastatic disease, serial determinations of CA 15.3 serum levels were made in 444 disease-free patients after surgery, during 36 months of follow-up. The results were compared with carcinoembryonic antigen (CEA) and tissue polypeptide antigen (TPA). The study found CA 15.3 to be more sensitive as an early indicator of relapse than CEA or TPA; moreover, simultaneous determination of the other markers offers no information additional to that obtained by CA 15.3 alone. |
| Databáze: | OpenAIRE |
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