Sleeve gastrectomy leads to Helicobacter pylori eradication
| Autor: | Ibrahim Matter, Omer Goldstein, Dean Keren, Edy Stermer, Tova Rainis, Alexandra Lavy |
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| Rok vydání: | 2008 |
| Předmět: |
Adult
Male medicine.medical_specialty Sleeve gastrectomy Adolescent Endocrinology Diabetes and Metabolism medicine.medical_treatment Gastroenterology Asymptomatic Helicobacter Infections Young Adult Clinical Protocols Gastrectomy Internal medicine medicine Humans Urea Aged Retrospective Studies Breath test Laparoscopic sleeve gastrectomy Nutrition and Dietetics Routine screening biology medicine.diagnostic_test Helicobacter pylori business.industry Stomach Middle Aged biology.organism_classification Surgery Obesity Morbid medicine.anatomical_structure Treatment Outcome Breath Tests Female medicine.symptom business |
| Zdroj: | Obesity surgery. 19(6) |
| ISSN: | 0960-8923 |
| Popis: | The role of Helicobacter pylori (HP) in patients scheduled and undergoing laparoscopic sleeve gastrectomy (LSG) has not been previously evaluated. Included were obese patients presenting to our institution for LSG over 24 months. All patients had presurgical HP breath test, and the symptomatic ones received triple therapy with symptom follow-up. Post surgery, all excluded stomachs were evaluated for HP, and those that were positive performed a second 13C-urea breath test (UBT) 3 months later. Forty patients underwent LSG. Male to female sex ratio was 1:3; mean age—42 years; mean weight—122 kg; and mean BMI of 43.4 kg/m2. Presurgical HP was positive in 15 (37.5%) patients (11 symptomatic and four asymptomatic). Only these 11 patients were given HP eradication therapy and all experienced complete subsequent symptom resolution. HP was detected in 17 out of the 40 (42.5%) cases of excluded stomachs. All performed a 13C-UBT 3 months post operation and only three (17.6%) tested positive. HP infection is frequent in biopsies from patients with previous LSG and the majority of follow-up 13C-UBT were negative. In our small initial sample, we treated only symptomatic patients preoperatively. Routine screening for HP for all LSG patients and/or treatment for all positive ones would subject patients to expensive and unnecessary investigations. We propose that this stomach-reducing, pylorus-preserving surgery might even lead to HP eradication. The clinical implications of HP and this gastrectomy for a non-neoplastic, non-peptic indication deserve further study. |
| Databáze: | OpenAIRE |
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