The preprotein translocase of the outer mitochondrial membrane: receptors and a general import pore
| Autor: | Chris Meisinger, Michael T. Ryan, Jan Brix, Nikolaus Pfanner, Kirstin Model |
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| Rok vydání: | 1999 |
| Předmět: |
Pore complex
Macromolecular Substances Translocase of the outer membrane TIM/TOM complex Permeability Cellular and Molecular Neuroscience Bacterial Proteins Mitochondrial Precursor Protein Import Complex Proteins Translocase Outer membrane efflux proteins Molecular Biology Adenosine Triphosphatases Pharmacology SecA Proteins biology Chemistry Escherichia coli Proteins Fungi Membrane Proteins Membrane Transport Proteins Intracellular Membranes Cell Biology Mitochondria Cell biology Protein Subunits Protein Transport Translocase of the inner membrane biology.protein Molecular Medicine Carrier Proteins Bacterial outer membrane Intermembrane space SEC Translocation Channels |
| Zdroj: | Scopus-Elsevier ResearcherID |
| ISSN: | 1420-9071 1420-682X |
| DOI: | 10.1007/s000180050028 |
| Popis: | Cytosol-synthesized preproteins destined for the mitochondria are transported across the outer membrane by the translocase of the mitochondrial outer membrane (TOM complex). This dynamic transport machinery can be divided into receptors that recognize preprotein targeting signals and components of the general import pore complex that mediate preprotein transport across the outer membrane. This review focuses on recent studies dealing with the central questions regarding the pore-forming subunits, and architecture and gating of the translocation channel of the outer membrane. |
| Databáze: | OpenAIRE |
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