Barriers to Care and 1-Year Mortality Among Newly Diagnosed HIV-Infected People in Durban, South Africa
| Autor: | Christine E. Chaisson, Ingrid V. Bassett, Tessa Govender, Moses J E Flash, Kenneth A. Freedberg, Elena Losina, Rochelle P. Walensky, Laura M. Bogart, Janet Giddy, Sharon M. Coleman, Douglas Ross |
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| Jazyk: | angličtina |
| Rok vydání: | 2016 |
| Předmět: |
0301 basic medicine
HIV/TB coinfection Adult Male Anti-HIV Agents Population HIV Infections Health Services Accessibility 03 medical and health sciences Social support barriers to care South Africa 0302 clinical medicine Interquartile range Health care Medicine Humans Tuberculosis Pharmacology (medical) 030212 general & internal medicine Lost to follow-up education Randomized Controlled Trials as Topic education.field_of_study business.industry Proportional hazards model Coinfection Hazard ratio Social Support Clinical Science 030112 virology mortality Confidence interval CD4 Lymphocyte Count Infectious Diseases Health Care Surveys Optometry Patient Compliance Female Lost to Follow-Up business Demography |
| Zdroj: | Journal of Acquired Immune Deficiency Syndromes (1999) |
| ISSN: | 1944-7884 1525-4135 |
| Popis: | Background Prompt entry into HIV care is often hindered by personal and structural barriers. Our objective was to evaluate the impact of self-perceived barriers to health care on 1-year mortality among newly diagnosed HIV-infected individuals in Durban, South Africa. Methods Before HIV testing at 4 outpatient sites, adults (≥18 years) were surveyed regarding perceived barriers to care including (1) service delivery, (2) financial, (3) personal health perception, (4) logistical, and (5) structural. We assessed deaths via phone calls and the South African National Population Register. We used multivariable Cox proportional hazards models to determine the association between number of perceived barriers and death within 1 year. Results One thousand eight hundred ninety-nine HIV-infected participants enrolled. Median age was 33 years (interquartile range: 27-41 years), 49% were females, and median CD4 count was 192/μL (interquartile range: 72-346/μL). One thousand fifty-seven participants (56%) reported no, 370 (20%) reported 1-3, and 460 (24%) reported >3 barriers to care. By 1 year, 250 [13%, 95% confidence interval (CI): 12% to 15%] participants died. Adjusting for age, sex, education, baseline CD4 count, distance to clinic, and tuberculosis status, participants with 1-3 barriers (adjusted hazard ratio: 1.49, 95% CI: 1.06 to 2.08) and >3 barriers (adjusted hazard ratio: 1.81, 95% CI: 1.35 to 2.43) had higher 1-year mortality risk compared with those without barriers. Conclusions HIV-infected individuals in South Africa who reported perceived barriers to medical care at diagnosis were more likely to die within 1 year. Targeted structural interventions, such as extended clinic hours, travel vouchers, and streamlined clinic operations, may improve linkage to care and antiretroviral therapy initiation for these people. |
| Databáze: | OpenAIRE |
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