Structural polypeptides of Machupo virus
| Autor: | Rosato Rr, J. D. Gangemi, Johnson Em, G. A. Eddy, E. V. Connell |
|---|---|
| Rok vydání: | 1978 |
| Předmět: |
Arenavirus
Glycosylation biology viruses Protein species Virion biology.organism_classification Virology Virus Molecular Weight chemistry.chemical_compound Glycosylated protein Viral Proteins Glycolipid chemistry Biochemistry Mole Electrophoresis Polyacrylamide Gel Arenaviridae Peptides Pathogen Arenaviruses New World Glycoproteins |
| Zdroj: | The Journal of general virology. 41(1) |
| ISSN: | 0022-1317 |
| Popis: | Summary The structural proteins of an arenavirus pathogen, Machupo virus, were compared to the structural proteins of two previously characterized non-pathogenic arenaviruses, Pichinde and Tacaribe, in SDS-polyacrylamide gels. Similarities in mol. wt. of the major structural proteins from both pathogenic and non-pathogenic viruses were apparent; however, some differences in the number of glycosylation properties of minor proteins were observed. Machupo virions contain two major protein species. The most prominent is a non-glycosylated protein with a mol. wt. of 68000, while the other was a glycosylated protein with a mol. wt. of 41000. Minor amounts of other proteins (mol. wt. 84000, 74000, 50000 and 15000) and a glycolipid were also observed. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|