Cytogenetic analysis in lymphocytes from radiation workers exposed to low level of ionizing radiation in radiotherapy, CT-scan and angiocardiography units
| Autor: | Sayyed Mahmood Latifi, Elahe Salari, Alihossein Saberi |
|---|---|
| Rok vydání: | 2013 |
| Předmět: |
Adult
Male Health Toxicology and Mutagenesis medicine.medical_treatment Ring chromosome Mutagen Biology Radiation Dosage medicine.disease_cause Ionizing radiation Young Adult Dicentric chromosome Occupational Exposure Radiation Ionizing Genetics Acentric fragment medicine Humans Lymphocytes Angiocardiography Chromosome Aberrations Radiology Department Hospital Radiotherapy medicine.diagnostic_test business.industry Personnel Hospital Radiation therapy Angiography Female Tomography X-Ray Computed Nuclear medicine business |
| Zdroj: | Mutation Research/Genetic Toxicology and Environmental Mutagenesis. 750:92-95 |
| ISSN: | 1383-5718 |
| Popis: | Ionizing radiation is known as a classical mutagen capable of inducing various kinds of stable and unstable chromosomal aberrations. The percentage of cells with chromosomal aberrations was analyzed in peripheral blood lymphocytes of occupationally exposed workers in radiotherapy, CT-scan, angiography and healthy controls. The incidence of all types of aberrations (gap, acentric fragment, dicentric and ring) in exposed subjects were higher than those observed in healthy controls (P=0.0001). However, the frequency of aberrant cells with dicentric and ring chromosome in exposed subjects were not significantly different from those in controls. To see whether there is a significant difference in the incidence of chromosomal aberrations among three groups, they were compared for all types of observed aberrations. No significant difference was found between radiotherapy and CT-scan groups (P=0.838). The percentage of aberrant cells observed, for angiography groups were significantly higher than radiotherapy (P=0.0001) and CT-scan (P=0.0001) group. Taken together these data suggest that the cumulative effects of low level chronic exposure to ionizing radiation is higher for those who occupationally exposed in angiography. |
| Databáze: | OpenAIRE |
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