Prognostic value of combined magnetic resonance myocardial perfusion imaging and late gadolinium enhancement

Autor: Rungroj Krittayaphong, Adisak Maneesai, Suthipol Udompanturak, Vithaya Chaithiraphan
Rok vydání: 2011
Předmět:
Gadolinium DTPA
Male
Time Factors
Myocardial Infarction
Myocardial Ischemia
Contrast Media
Coronary Artery Disease
Kaplan-Meier Estimate
Coronary artery disease
Risk Factors
Myocardial infarction
Angioplasty
Balloon
Coronary
Coronary Artery Bypass
Cardiac imaging
Ejection fraction
medicine.diagnostic_test
Myocardial Perfusion Imaging
Middle Aged
Prognosis
Thailand
Magnetic Resonance Imaging
Hospitalization
Stroke
medicine.anatomical_structure
cardiovascular system
Cardiology
Female
Radiology
Cardiology and Cardiovascular Medicine
medicine.medical_specialty
Risk Assessment
Myocardial perfusion imaging
Coronary circulation
Predictive Value of Tests
Internal medicine
Coronary Circulation
medicine
Humans
Radiology
Nuclear Medicine and imaging
cardiovascular diseases
Angina
Unstable
Aged
Proportional Hazards Models
Heart Failure
Unstable angina
business.industry
medicine.disease
Radiography
Heart failure
business
Zdroj: The international journal of cardiovascular imaging. 27(5)
ISSN: 1875-8312
Popis: Late gadolinium enhancement (LGE) and myocardial perfusion study by cardiac magnetic resonance (CMR) have a diagnostic and prognostic value in patients with suspected coronary artery disease (CAD). The purpose of this study was to determine the prognostic value of combined myocardial perfusion CMR and LGE in patients with known or suspected CAD. We studied patients with known or suspected CAD. All patients underwent CMR for functional study, myocardial perfusion and LGE. Myocardial ischemia by CMR was defined as a perfusion defect in patients without LGE or a perfusion defect beyond the LGE area. Patients were followed up for cardiovascular outcomes including hard cardiac events (cardiac death or non-fatal myocardial infarction) and major adverse cardiac events (MACE) which included cardiac death, non-fatal myocardial infarction, hospitalization for unstable angina, and heart failure. There were a total of 587 men and 645 women. Average age was 64.6 ± 11.1 years. LGE was detected in 326 patients (26.5%). Myocardial ischemia by CMR was detected in 423 patients (34.3%). Average follow-up duration was 34.9 ± 15.6 months. Univariate analysis showed that age, diabetes, use of beta blocker, left ventricular ejection fraction, left ventricular mass, wall motion abnormality, LGE, and myocardial ischemia are predictors for hard cardiac events and MACE. Multivariable analysis revealed that myocardial ischemia was the strongest predictor for hard cardiac events and MACE. Other independent predictors were age, use of beta blocker, and left ventricular mass. Myocardial ischemia by CMR has an incremental prognostic value for cardiac events in patients with known or suspected CAD.
Databáze: OpenAIRE
Externí odkaz: