| Popis: |
Faculty of Chemical and Metallurgical Engineering, Department of Bioengineering, Yildiz Technical University, Esenler, Istanbul, Turkey E-mail: syucel@yildiz.edu.tr, yuce.sevil@gmail.com Manuscript received online 26 April 2019, revised and accepted 20 July 2019 In this study, it was aimed to produce by melt-quenching method non-additive (SiO2 -Na2O-P2O5 -CaO) and ion additive (SiO2 - Na2O-P2O5 -CaO-MgO-ZnO-K2O-CuO) bioactive glasses (different forms; powder and granule). In vitro bioactivity and biodegradability properties of bioactive glasses in different forms (granule and powder) were examined with Simulated Body Fluid (SBF) and Tris-HCl analyses. Chemical bonds structures and surface morphology analysis of bioactive glasses (both additive and non-additive) were performed with FT-IR and SEM-EDS analysis before and after SBF immersion. SBF studies showed that both S53P4 bioactive glasses had similar bioactivity. As a results of Tris-HCl studies, in vitro biodegradability of bioactive glasses in powder forms are better than bioactive glasses in granule forms because of rapid raise of its pH value in Tris-HCl. However, ion additive S53P4 powder bioactive glass had more stable degradation behavior in comparison with non-additive S53P4 powder bioactive glass. |
