Octreotide and enterocutaneous fistula closure in neonates and children
| Autor: | Rafael Luque-Mialdea, Noela Carrera-Guermeur, Hilda J. Ramírez, Ángel Pantoja, Rosa M. Martín-Crespo |
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| Rok vydání: | 2015 |
| Předmět: |
Enterocutaneous fistula
Male medicine.medical_specialty Conservative management Case vignette Octreotide Conservative Treatment 03 medical and health sciences 0302 clinical medicine Gastrointestinal Agents medicine Intestinal Fistula Humans 030212 general & internal medicine Closure (psychology) Intensive care medicine Child Gastrointestinal agent Treatment regimen business.industry Infant Newborn Infant Somatostatin Child Preschool Pediatrics Perinatology and Child Health 030211 gastroenterology & hepatology business Infant Premature medicine.drug |
| Zdroj: | European journal of pediatrics. 175(3) |
| ISSN: | 1432-1076 |
| Popis: | Enterocutaneous fistula and its conservative management still pose a challenge for the surgeon. The use of octreotide and somatostatin in neonates and children as adjunctive therapy in the conservative management of this condition, leads to major controversy regarding its efficacy. Therefore, we conducted an extensive literature review of published articles regarding the use of somatostatin and its analogues in the treatment of enterocutaneous fistula in neonates and children. Our review is then presented together with a case vignette and discusses the different practical aspects of the treatment with these drugs. Conclusion: The major diversity in treatment regimens among published studies makes outcomes difficult to compare. However, given the results of the different cases reported in the literature and of our own experience, we suggest a possible beneficial effect of octreotide and somatostatin on closure of enterocutaneous fistula in these patients. |
| Databáze: | OpenAIRE |
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